抽动秽语综合征共患注意缺陷多动障碍男性儿童的反应抑制和精细调节Response inhibition and fine-motor coordination in male children with Tourette syndrome comorbid attention-deficit/hyperactivity disorder
朱云程;江茜茜;刘丽;杜文永;曹爱爱;张郦;鞠康;李欣馨;李国海;季卫东;
摘要(Abstract):
目的:了解抽动秽语综合征(TS)与注意缺陷多动障碍(ADHD)可能存在的神经心理缺陷的异同点。方法:选择符合疾病和有关健康问题的国际统计分类第十次修订本(ICD-10)诊断标准的616岁门诊TS男性患儿30名,TS共病ADHD男性患儿36名,ADHD男性患儿36名以及性别、年龄、智商匹配的健康男性儿童50名作为对象,选择Stroop色-字干扰测验(Stroop)和Purdue钉板测验(Purdue)分别对反应抑制和精细调节经行评估。结果:ADHD组的Stroop测验得分高于TS、TS共病ADHD、正常对照组(均P<0.05),而TS和TS共病ADHD组间Stroop得分差异无统计学意义(P>0.05)。TS组、TS共病ADHD组以及ADHD组Purdue测验中得分均高于正常对照组(均P<0.05)。结论:男性ADHD儿童可能存在反应抑制缺陷,而TS与TS共病ADHD儿童未发现上述现象,反应抑制功能可能代表了TS神经发育过程中的补偿机制;TS、TS共病ADHD组以及ADHD组均存在精细调节缺陷。
关键词(KeyWords): 反应抑制;精细调节;抽动秽语综合征;注意缺陷多动障碍;共病
基金项目(Foundation):
作者(Authors): 朱云程;江茜茜;刘丽;杜文永;曹爱爱;张郦;鞠康;李欣馨;李国海;季卫东;
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